Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTP4A3Protein tyrosine phosphatase 4A3. (170 aa)    
Predicted Functional Partners:
rabggtb
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.765
pim3
Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
      
 0.654
LOC100706438
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.619
Wbp11
WW domain binding protein 11.
      
 0.577
TOMM20
Translocase of outer mitochondrial membrane 20.
      
 0.577
LOC100703030
Translocase of outer mitochondrial membrane 20b.
      
 0.577
C11orf96
Uncharacterized protein C11orf96 homolog.
      
 0.552
LOC100690604
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
  0.488
cnnm2
Cyclin and CBS domain divalent metal cation transport mediator 2b.
    
 
 0.488
I3JZ42_ORENI
Cyclin and CBS domain divalent metal cation transport mediator 4a.
    
 
 0.488
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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