Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100696566RHD domain-containing protein. (884 aa)    
Predicted Functional Partners:
LOC100697276
Serine/threonine-protein phosphatase.
    
 0.933
PPP3CA
Serine/threonine-protein phosphatase.
    
 0.933
I3IY44_ORENI
WD repeat domain 92.
    
 0.927
s1pr1
Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
  0.916
nfatc2
Nuclear factor of activated T cells 2a.
     
  0.916
LOC100690594
Serine/threonine-protein phosphatase.
    
 0.894
LOC100705072
Serine/threonine-protein phosphatase.
    
 0.894
LOC100709500
Sphingosine-1-phosphate receptor 5a; Belongs to the G-protein coupled receptor 1 family.
     
  0.836
LOC100709580
Sphingosine-1-phosphate receptor 3a; Belongs to the G-protein coupled receptor 1 family.
     
  0.629
LOC100706924
DnaJ (Hsp40) homolog, subfamily C, member 18.
    
 0.626
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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