Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptpmt1Protein tyrosine phosphatase mitochondrial 1. (182 aa)    
Predicted Functional Partners:
tamm41
Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.
      
 0.749
I3JWC4_ORENI
ATP/GTP binding protein-like 2.
      
 0.675
rapsn
Receptor-associated protein of the synapse, 43kD.
      
 0.675
thap4
THAP domain containing 4.
   
  
 0.637
commd3
COMM domain containing 3.
   
  
 0.635
Slc39a13
Solute carrier family 39 member 13.
   
  
 0.610
ndufs3
NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family.
 
 
  
 0.600
taz
Tafazzin family protein; Belongs to the taffazin family.
      
 0.577
pgs1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial.
      
 0.574
dolpp1
Dolichyldiphosphatase 1.
      
 0.559
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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