sncg protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

sncg

Gamma-synuclein; Belongs to the synuclein family. (124 aa)

Predicted Functional Partners:

Prkn

0.843

sncaip

0.782

sncb

0.776

park7

0.683

psmc3

0.681

TPPP

0.626

psmc4

0.618

sqstm1

0.612

LOC100709337

0.611

LOC100707019

0.594

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100707019	sncg	ENSONIP00000017280	ENSONIP00000008842	Uncharacterized protein.	Gamma-synuclein; Belongs to the synuclein family.	0.594
LOC100709337	sncg	ENSONIP00000044310	ENSONIP00000008842	Crystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family.	Gamma-synuclein; Belongs to the synuclein family.	0.611
Prkn	park7	ENSONIP00000009000	ENSONIP00000056092	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Parkinson protein 7.	0.997
Prkn	psmc3	ENSONIP00000009000	ENSONIP00000021514	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.989
Prkn	psmc4	ENSONIP00000009000	ENSONIP00000027200	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.980
Prkn	sncaip	ENSONIP00000009000	ENSONIP00000017351	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Synuclein, alpha interacting protein.	0.999
Prkn	sncg	ENSONIP00000009000	ENSONIP00000008842	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Gamma-synuclein; Belongs to the synuclein family.	0.843
Prkn	sqstm1	ENSONIP00000009000	ENSONIP00000000126	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Sequestosome 1.	0.989
TPPP	sncg	ENSONIP00000003826	ENSONIP00000008842	Tubulin polymerization promoting protein.	Gamma-synuclein; Belongs to the synuclein family.	0.626
TPPP	sqstm1	ENSONIP00000003826	ENSONIP00000000126	Tubulin polymerization promoting protein.	Sequestosome 1.	0.474
park7	Prkn	ENSONIP00000056092	ENSONIP00000009000	Parkinson protein 7.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.997
park7	sncaip	ENSONIP00000056092	ENSONIP00000017351	Parkinson protein 7.	Synuclein, alpha interacting protein.	0.528
park7	sncg	ENSONIP00000056092	ENSONIP00000008842	Parkinson protein 7.	Gamma-synuclein; Belongs to the synuclein family.	0.683
park7	sqstm1	ENSONIP00000056092	ENSONIP00000000126	Parkinson protein 7.	Sequestosome 1.	0.502
psmc3	Prkn	ENSONIP00000021514	ENSONIP00000009000	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.989
psmc3	psmc4	ENSONIP00000021514	ENSONIP00000027200	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.999
psmc3	sncg	ENSONIP00000021514	ENSONIP00000008842	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	Gamma-synuclein; Belongs to the synuclein family.	0.681
psmc4	Prkn	ENSONIP00000027200	ENSONIP00000009000	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.980
psmc4	psmc3	ENSONIP00000027200	ENSONIP00000021514	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.999
psmc4	sncg	ENSONIP00000027200	ENSONIP00000008842	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	Gamma-synuclein; Belongs to the synuclein family.	0.618