Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtbpMDM2 binding protein. (869 aa)    
Predicted Functional Partners:
ENSONIP00000069434
annotation not available
    
 0.972
ticrr
Treslin_N domain-containing protein.
   
 0.882
topbp1
DNA topoisomerase II binding protein 1.
   
 
 0.857
mdm4
MDM4 regulator of p53; Belongs to the MDM2/MDM4 family.
    
 0.831
ENSONIP00000024927
RecQ helicase-like 4.
   
 
 0.769
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 
 0.703
I3J3L9_ORENI
Ribonuclease P and MRP subunit p25, b.
      
 0.694
lg22h1orf109
C19h1orf109 homolog (H. sapiens).
      
 0.687
magoh
Mago homolog, exon junction complex subunit.
    
 0.674
dbf4
DBF4 zinc finger.
   
 0.672
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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