Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slc6a3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (627 aa)    
Predicted Functional Partners:
LOC100691213
Uncharacterized protein; Belongs to the synuclein family.
    
 
 0.869
LOC100705041
Protein kinase domain-containing protein.
     
  0.836
drd2
Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family.
    
 0.801
drd3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
    
 0.801
nfatc2
Nuclear factor of activated T cells 2a.
      
 0.695
th
Tyrosine hydroxylase.
   
  
 0.682
Slc18a2
Solute carrier family 18 member 2.
   
 
 0.665
ENSONIP00000066161
annotation not available
     
  0.630
LOC100707324
Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2.
     
  0.630
stx2
Syntaxin 2b; Belongs to the syntaxin family.
    
 0.622
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.