Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wdhd1WD repeat and HMG-box DNA binding protein 1. (1144 aa)    
Predicted Functional Partners:
pola1
DNA polymerase.
   
 
 0.993
mcm6
DNA helicase; Belongs to the MCM family.
   
 
 0.992
mcm4
DNA helicase; Belongs to the MCM family.
   
 
 0.991
mcm2
DNA helicase; Belongs to the MCM family.
   
 
 0.991
mcm5
DNA helicase; Belongs to the MCM family.
   
 
 0.990
mcm3
DNA helicase; Belongs to the MCM family.
   
 
 0.986
chtf18
AAA domain-containing protein.
   
 
 0.983
prim2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
   
 
 0.981
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 
 0.977
timeless
Timeless circadian clock.
   
 
 0.974
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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