Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dbx1Developing brain homeobox 1a. (319 aa)    
Predicted Functional Partners:
lrp4
Low density lipoprotein receptor-related protein 4.
      
 0.728
slc6a5
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.715
htatip2
HIV-1 Tat interactive protein 2.
   
  
 0.670
Prmt3
Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
      
 0.648
LOC100700201
EGF-like domain-containing protein.
      
 0.599
LOC100691684
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
      
 0.483
LOC100707403
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
      
 0.483
mrpl16
Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family.
   
  
 0.468
B3GNT3
Hexosyltransferase.
      
 0.452
b3gnt3
Hexosyltransferase.
      
 0.452
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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