STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pms1PMS1 homolog 1, mismatch repair system component. (897 aa)    
Predicted Functional Partners:
msh2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.989
Mlh1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
  
 
0.988
msh6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.985
I3KAM2_ORENI
MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.968
Msh4
MutS homolog 4.
 
 0.965
msh5
MutS homolog 5.
 
 0.955
Exo1
Exonuclease 1.
   
 0.926
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.873
pms2
PMS1 homolog 2, mismatch repair system component.
  
0.847
Mlh3
MutL homolog 3 (E. coli).
  
 
0.826
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.