Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sde2SDE2 telomere maintenance homolog (S. pombe). (416 aa)    
Predicted Functional Partners:
fam32a
Family with sequence similarity 32 member A.
    
 0.992
cdc40
Cell division cycle 40 homolog (S. cerevisiae).
    
 0.988
slu7
SLU7 homolog, splicing factor.
   
 0.986
crnkl1
Crooked neck pre-mRNA splicing factor 1.
    
 
 0.985
syf2
SYF2 pre-mRNA-splicing factor.
    
 0.985
ppil1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
  0.978
prkrip1
PRKR interacting protein 1.
     
 0.975
cactin
Cactin.
    
 0.971
ccdc12
Coiled-coil domain containing 12.
    
  0.964
nkap
NFKB activating protein.
    
 0.960
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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