Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JJV7_ORENIPotassium channel tetramerization domain containing 1. (257 aa)    
Predicted Functional Partners:
ENSONIP00000065150
annotation not available
 
      0.847
tfap2d
Transcription factor AP-2 delta (activating enhancer binding protein 2 delta).
   
 0.632
tfap2b
Transcription factor AP-2 beta.
   
 0.630
tfap2e
Transcription factor AP-2 epsilon.
   
 0.630
tfap2c
Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma).
   
 0.630
tfap2a
Transcription factor AP-2 alpha.
   
 0.630
ENSONIP00000061996
annotation not available
    
 
 0.618
ube2i
Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.618
kctd2
Potassium channel tetramerization domain containing 2.
    
 
 0.584
coq6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
   
  
 0.496
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.