Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
I3JJY4_ORENIKinase; Belongs to the inositol phosphokinase (IPK) family. (404 aa)    
Predicted Functional Partners:
ippk
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
     
 0.979
LOC100698911
Multiple inositol-polyphosphate phosphatase 1a; Belongs to the histidine acid phosphatase family.
     
 0.958
LOC100700292
Uncharacterized protein; Belongs to the histidine acid phosphatase family.
     
 0.958
INPP5A
Inositol polyphosphate-5-phosphatase A.
     
 0.938
LOC100700932
Inositol polyphosphate-5-phosphatase L.
     
 0.938
LOC100691819
Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family.
     
 0.935
itpk1
Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family.
     
 0.935
plcd3
Phosphoinositide phospholipase C.
    
 0.933
LOC100705971
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.930
itpka
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.930
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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