Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ssx2ipSynovial sarcoma, X breakpoint 2 interacting protein b. (576 aa)    
Predicted Functional Partners:
LOC100689978
Synovial sarcoma, X breakpoint 2 interacting protein a.
     
  0.916
ENSONIP00000079612
Afadin- and alpha-actinin-binding protein isoform X1.
     
  0.916
I3KFA3_ORENI
Afadin, adherens junction formation factor a.
    
  0.870
ENSONIP00000048171
annotation not available
    
  0.870
actn3
Actinin alpha 3b.
     
 0.776
LOC100696265
Actinin, alpha 1.
     
 0.776
LOC100702502
Actinin, alpha 2b.
     
 0.776
ACTN4
Actinin alpha 4.
     
 0.776
I3JVP4_ORENI
Uncharacterized protein.
     
  0.585
fto
FTO alpha-ketoglutarate dependent dioxygenase.
     
 0.570
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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