Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
n4bp1Nedd4 binding protein 1. (979 aa)    
Predicted Functional Partners:
LOC100711295
Si:ch73-252i11.1.
    
 
 0.834
ENSONIP00000047919
Ubiquitin B.
    
 
 0.758
ikbkg
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
  0.692
atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1.
      
 0.691
LOC100690293
Ubiquitin-NEDD8-like protein RUB2.
    
 
 0.672
LOC100711516
Ubiquitin-like protein Nedd8.
    
 
 0.672
LOC100702139
Uncharacterized protein; Belongs to the peptidase C14A family.
     
 0.668
LOC109194206
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
     
 0.621
I3KF49_ORENI
Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
     
 0.612
sec62
SEC62 homolog, preprotein translocation factor.
      
 0.586
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (22%) [HD]