STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100703553Notch receptor 1a. (2480 aa)    
Predicted Functional Partners:
LOC106098755
Recombination signal binding protein for immunoglobulin kappa J region a.
    
 0.991
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.991
LOC100699141
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.980
NCSTN
Nicastrin.
    
 0.980
jag1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.980
LOC100710579
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.980
LOC100697238
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.967
LOC100710620
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.967
aph1a
APH1B gamma secretase subunit.
    
 0.965
maml1
Mastermind-like transcriptional coactivator 1.
   
 0.958
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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