Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rtcbRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (505 aa)    
Predicted Functional Partners:
ddx1
DEAD (Asp-Glu-Ala-Asp) box helicase 1.
   
 0.997
Fam98b
Family with sequence similarity 98 member B.
   
 0.997
zbtb8os
Zinc finger and BTB domain containing 8 opposite strand.
 
 0.995
Lg16h2orf49
Si:dkeyp-118h3.6.
    
 0.995
I3JB52_ORENI
Family with sequence similarity 98 member A.
    
 0.992
rtraf
RNA transcription, translation and transport factor.
   
 0.976
ENSONIP00000036220
RNA transcription, translation and transport factor protein-like.
   
 0.976
rtca
RNA 3'-terminal phosphate cyclase.
  
  
 0.911
pyroxd1
Pyridine nucleotide-disulphide oxidoreductase domain 1.
   
 
 0.864
LOC100700754
Uncharacterized protein.
    
 0.858
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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