Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP8Rho GTPase activating protein 8. (430 aa)    
Predicted Functional Partners:
LOC100697014
Uncharacterized protein.
   
 0.645
LOC100702504
Rho GTPase activating protein 22.
     
 0.526
LOC100711995
Rho GTPase activating protein 22.
     
 0.526
LOC100698524
Uncharacterized protein.
    
   0.463
LOC100704272
SH3-domain GRB2-like 1b.
    
   0.463
LOC100692766
SH3-domain GRB2-like 3a.
    
   0.463
LOC100692909
SH3 domain containing GRB2 like 2a, endophilin A1.
    
   0.463
gdap2
Ganglioside induced differentiation associated protein 2.
      
 0.430
I3KW58_ORENI
Tudor domain containing 9.
      
 0.409
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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