Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
I3JKT8_ORENIFilamin C, gamma b (actin binding protein 280). (2767 aa)    
Predicted Functional Partners:
Itgb5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.865
fblim1
Filamin binding LIM protein 1.
   
 0.864
LOC100699105
Integrin beta; Belongs to the integrin beta chain family.
    
 0.855
LOC100692535
Integrin beta; Belongs to the integrin beta chain family.
    
 0.841
itgb3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.835
Itgb8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.834
itgb6
Integrin beta; Belongs to the integrin beta chain family.
    
 0.831
itgb1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.826
itgb4
Integrin beta.
    
 0.822
itga4
Integrin alpha 4; Belongs to the integrin alpha chain family.
   
 0.730
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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