Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
socs2Suppressor of cytokine signaling 2. (201 aa)    
Predicted Functional Partners:
eloc
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.992
socs1
Uncharacterized protein.
    
0.978
LOC100703753
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.971
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.971
socs5
Suppressor of cytokine signaling 5b.
     
0.967
LOC100704232
Uncharacterized protein.
    
0.965
LOC100702935
Suppressor of cytokine signaling 1b.
     
0.959
I3JU14_ORENI
Elongin B.
    
 0.959
elob
Ubiquitin-like domain-containing protein.
    
 0.959
ghr
Growth hormone receptor type 2.
    
 0.942
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.