STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JKV8_ORENIEpidermal growth factor receptor pathway substrate 8a. (811 aa)    
Predicted Functional Partners:
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.742
LOC100693503
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 0.742
ABI1
Abl-interactor 1a.
   
 
 0.707
LOC100703100
Abl-interactor 1b.
   
 
 0.707
mpp1
Membrane protein, palmitoylated 1; Belongs to the MAGUK family.
   
 0.681
LOC100711936
BAI1 associated protein 2.
    
 
 0.649
LOC100696811
BAI1-associated protein 2a.
    
 
 0.649
sos2
Son of sevenless homolog 2 (Drosophila).
   
 
 0.624
Sos1
Son of sevenless homolog 1 (Drosophila).
   
 
 0.624
twf1
Twinfilin actin-binding protein 1a.
     
 0.620
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.