Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mfsd8Major facilitator superfamily domain containing 8. (492 aa)    
Predicted Functional Partners:
cln8
CLN8 transmembrane ER and ERGIC protein.
      
 0.879
LOC102080728
MFS domain-containing protein.
     
  0.866
LOC102082099
Major facilitator superfamily domain-containing protein 8.
     
  0.866
LOC100689844
Battenin.
    
 
 0.860
cln5
CLN5 intracellular trafficking protein.
      
 0.841
mpl
MPL proto-oncogene, thrombopoietin receptor.
    
 0.834
ppt1
Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).
      
 0.798
abhd18
Abhydrolase domain containing 18.
      
 0.724
tpp1
Tripeptidyl peptidase I.
      
 0.719
LOC100705613
Cathepsin F; Belongs to the peptidase C1 family.
      
 0.685
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (6%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.