Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
slc45a2Solute carrier family 45 member 2. (568 aa)    
Predicted Functional Partners:
tyrp1
Tyrosinase related protein 1.
   
  
 0.812
Oca2
Oculocutaneous albinism II.
      
 0.806
ENSONIP00000073014
Solute carrier family 24 member 5.
   
  
 0.782
gpr143
G protein-coupled receptor 143.
   
  
 0.777
LOC100711224
Tyrosinase-related protein 1b.
   
  
 0.719
mc1r
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.713
psmb2
Proteasome subunit beta.
      
 0.693
LOC100711455
Premelanosome protein a.
   
  
 0.693
herc3
HECT and RLD domain containing E3 ubiquitin protein ligase 3.
      
 0.692
spr
Sepiapterin reductase b.
      
 0.679
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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