STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JLB3_ORENIRho GTPase activating protein 39. (1007 aa)    
Predicted Functional Partners:
LOC100704372
Ras homolog family member F.
    
  0.530
LOC100697014
Uncharacterized protein.
     
0.525
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.525
cdc42
Cell division cycle 42.
    
 0.521
I3K885_ORENI
Uncharacterized protein; Belongs to the intermediate filament family.
    
  0.472
LOC100691959
Lamin L3; Belongs to the intermediate filament family.
    
  0.472
lmnb2
Lamin B2; Belongs to the intermediate filament family.
    
  0.472
lmna
Lamin A; Belongs to the intermediate filament family.
    
  0.472
ipo5
Karyopherin (importin) beta 3.
    
 
 0.468
rpl18
60S ribosomal protein L18; Component of the large ribosomal subunit.
    
 0.459
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.