Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100711859Retinal homeobox gene 3. (315 aa)    
Predicted Functional Partners:
I3JLM4_ORENI
Iroquois homeobox 1b.
    
 
 0.599
ENSONIP00000072961
Forkhead box G1a.
   
 0.533
I3JR68_ORENI
NME/NM23 family member 8; Belongs to the NDK family.
    
  0.502
LOC100700541
Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
   
 
 0.496
LOC100693993
Nuclear factor, interleukin 3 regulated, member 5.
      
 0.491
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 
 0.488
Atoh7
Atonal bHLH transcription factor 7.
      
 0.474
rorb
RAR-related orphan receptor B.
      
 0.456
LOC100705377
Opsin 7, group member a; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
    
 
 0.456
LOC100692739
Crystallin beta gamma X; Belongs to the beta/gamma-crystallin family.
      
 0.453
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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