Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dnajc21DnaJ heat shock protein family (Hsp40) member C21. (527 aa)    
Predicted Functional Partners:
nmd3
60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.
   
 
 0.886
LOC100711208
Proliferation-associated 2G4, b.
   
 
 0.861
pa2g4
Proliferation-associated 2G4, a.
   
 
 0.861
znf622
Zinc finger protein 622.
   
 
 0.807
retreg1
Reticulophagy regulator 1.
   
 
 0.807
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
  0.779
oplah
5-oxoprolinase, ATP-hydrolysing.
     
  0.779
pum1
Pumilio RNA-binding family member 1.
    
 
 0.773
mrps18b
Mitochondrial ribosomal protein S18B.
    
   0.770
dnajc2
DnaJ (Hsp40) homolog, subfamily C, member 2.
   
 
 0.743
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (18%) [HD]