Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100704334Low density lipoprotein receptor adaptor protein 1a. (311 aa)    
Predicted Functional Partners:
dab2
DAB adaptor protein 2.
     
 0.928
ldlrap1
Low density lipoprotein receptor adaptor protein 1b.
     
  0.916
ENSONIP00000065900
Si:dkey-19b23.8.
     
  0.916
LOC100692480
Si:dkey-71h2.2.
     
  0.915
ldlr
Low density lipoprotein receptor a.
    
 0.914
LOC100711575
Low-density lipoprotein receptor isoform X2.
    
 0.914
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
      
 0.776
stn1
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
    
   0.762
I3JQH3_ORENI
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.
    
 0.754
LOC100712136
Uncharacterized protein.
    
 0.754
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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