Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
zc3h4Zinc finger CCCH-type containing 4. (1425 aa)    
Predicted Functional Partners:
twf2
WD repeat domain 82.
   
 0.876
LOC100709494
Twinfilin actin-binding protein 2b.
   
 0.876
nudt21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
    
 0.860
cpsf1
Cleavage and polyadenylation specific factor 1.
   
 0.858
sympk
Symplekin.
   
 0.852
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.850
LOC100706148
FIP1 like 1b (S. cerevisiae).
    
 0.847
cstf3
Cleavage stimulation factor, 3' pre-RNA, subunit 3.
    
 0.846
cstf2
Cleavage stimulation factor, 3' pre-RNA, subunit 2.
   
 0.845
cstf1
Cleavage stimulation factor, 3' pre-RNA, subunit 1.
   
 0.840
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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