Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JLM4_ORENIIroquois homeobox 1b. (184 aa)    
Predicted Functional Partners:
wnt1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.786
six3
SIX homeobox 3a.
   
  
 0.732
irx6
Iroquois homeobox 6a.
   
 
 0.718
LOC100707005
Iroquois homeobox 4a.
   
 
 0.718
LOC100691448
Teashirt zinc finger homeobox 1.
    
 0.702
dlx1
Distal-less homeobox 1a.
   
 
 0.682
dlx2
Distal-less homeobox 2b.
   
 
 0.669
LOC100696648
Mohawk homeobox b.
    
 
 0.606
mkx
Mohawk homeobox a.
    
 
 0.606
LOC100711859
Retinal homeobox gene 3.
    
 
 0.599
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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