STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JM39_ORENISodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1889 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.990
LOC100691202
Sodium channel, voltage-gated, type I, beta a.
    
 0.916
LOC100698560
Sodium channel, voltage-gated, type II, beta.
   
 0.805
scn1b
Ig-like domain-containing protein.
    
 0.740
wdr35
WD repeat-containing protein 35.
    
 0.725
IFT122
Intraflagellar transport 122.
   
 0.715
ift140
Intraflagellar transport 140 homolog (Chlamydomonas).
    
 0.706
scn3b
Sodium channel, voltage-gated, type III, beta.
   
 0.689
LOC100698831
Sodium channel, voltage-gated, type IV, beta a.
    
 0.616
FUT9
Fucosyltransferase 9.
      
 0.607
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (18%) [HD]