Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITM2CIntegral membrane protein 2C. (259 aa)    
Predicted Functional Partners:
kndc1
Uncharacterized protein.
      
 0.574
gpr12
G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family.
      
 0.558
rrad
Ras-related associated with diabetes.
    
 
 0.556
npas4
Neuronal PAS domain protein 4a.
      
 0.551
slc35a5
Solute carrier family 35 member A5.
   
  
 0.550
adgrb1
Adhesion G protein-coupled receptor B1a; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.467
dnajb5
DnaJ heat shock protein family (Hsp40) member B5.
    
 
 0.463
pdzd11
PDZ domain containing 11.
   
  
 0.461
ndufs7
NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family.
    
 
 0.460
gak
Cyclin G associated kinase.
    
   0.441
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.