Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
I3JMD7_ORENIG protein-coupled receptor kinase interacting ArfGAP 1. (737 aa)    
Predicted Functional Partners:
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
   
 0.974
arhgef7
Rho guanine nucleotide exchange factor (GEF) 7a.
   
 0.974
LOC100696931
Rho guanine nucleotide exchange factor (GEF) 7b.
   
 0.974
LOC100706266
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.950
ENSONIP00000069782
Paxillin b.
    
 0.950
cdc42
Cell division cycle 42.
    
 0.902
LOC100702039
Uncharacterized protein LOC100702039.
   
 0.842
pak1
Non-specific serine/threonine protein kinase.
    
 0.829
PAK3
P21 (RAC1) activated kinase 3.
    
 0.829
PAK2
Non-specific serine/threonine protein kinase.
    
 0.820
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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