STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100706383Uncharacterized protein. (181 aa)    
Predicted Functional Partners:
vti1b
Vesicle transport through interaction with t-SNAREs 1B.
    
   0.669
p53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
   0.597
LOC100691194
Vesicle-associated membrane protein 8.
   
   0.592
stx8
t-SNARE coiled-coil homology domain-containing protein.
    
   0.586
ENSONIP00000050885
annotation not available
      
 0.493
Stx12
Syntaxin 12.
    
   0.469
stx7
Syntaxin 7-like; Belongs to the syntaxin family.
    
   0.469
ENSONIP00000029945
Syntaxin-12-like.
    
   0.469
ENSONIP00000077119
annotation not available
    
   0.469
dexi
Dexamethasone-induced protein.
      
 0.409
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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