Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC100696649Uncharacterized protein. (1399 aa)    
Predicted Functional Partners:
LOC100690173
Glutamate receptor, ionotropic, N-methyl D-aspartate 1b.
   
0.913
LOC100534577
Glutamate receptor, ionotropic, N-methyl D-aspartate 1a.
   
0.913
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
   
 0.754
nos1
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.692
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.664
LOC100693503
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 0.664
LOC100692877
Glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
     
 0.661
LOC100698622
Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b.
     
 
0.658
grin2a
Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a.
     
 
0.658
grin3b
Glutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb.
    
 0.654
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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