Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
txn2Thioredoxin 2. (172 aa)    
Predicted Functional Partners:
txnrd2
Thioredoxin reductase 2, tandem duplicate 1.
  
 0.995
prdx3
Peroxiredoxin 3.
  
 0.994
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.981
I3IZ02_ORENI
Arrestin_C domain-containing protein.
    
 0.973
txnip
Thioredoxin-interacting protein.
    
 0.972
LOC100704269
Si:ch211-1i11.3.
    
 0.945
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.945
LOC100692536
Thioredoxin; Belongs to the thioredoxin family.
   
 0.941
LOC100690837
Thioredoxin; Belongs to the thioredoxin family.
  
0.938
LOC100692805
Thioredoxin; Belongs to the thioredoxin family.
  
0.937
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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