STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
txn2Thioredoxin 2. (172 aa)    
Predicted Functional Partners:
I3IZ02_ORENI
Arrestin_C domain-containing protein.
    
 0.977
txnip
Thioredoxin-interacting protein.
    
 0.977
LOC100690837
Thioredoxin; Belongs to the thioredoxin family.
  
0.964
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.951
prdx3
Peroxiredoxin 3.
  
 0.919
LOC100702211
Peroxiredoxin 2.
  
 0.891
txnrd2
Thioredoxin reductase 2, tandem duplicate 1.
  
 0.888
LOC100702976
Thioredoxin reductase 3.
  
 0.876
LOC100703194
Peroxiredoxin 1.
  
 0.858
mrpl11
Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.
   
   0.847
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.