Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kizKizuna centrosomal protein. (730 aa)    
Predicted Functional Partners:
sclt1
Sodium channel and clathrin linker 1.
    
  0.965
fancm
Uncharacterized protein.
    
 
 0.765
tmtc4
Transmembrane O-mannosyltransferase targeting cadherins 4.
    
 0.653
prdm1
PR domain containing 1a, with ZNF domain.
    
  0.609
LOC100700828
PR domain containing 1b, with ZNF domain.
    
  0.609
LOC109194164
Uncharacterized protein.
    
  0.609
ap4e1
Adaptor related protein complex 4 subunit epsilon 1.
    
 
 0.581
mfhas1
Malignant fibrous histiocytoma amplified sequence 1.
    
 0.562
ENSONIP00000042766
annotation not available
  
 
  0.495
cuedc2
CUE domain containing 2.
      
 0.489
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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