Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC100696766Apoptosis inducing factor mitochondria associated 4. (538 aa)    
Predicted Functional Partners:
suox
Sulfite oxidase.
   
 0.804
LOC100691569
Cytochrome b5 reductase 4.
     
 0.688
ggnbp2
Gametogenetin binding protein 2.
   
 
 0.658
Acad8
Acyl-CoA dehydrogenase family, member 8.
   
 0.626
LOC100702604
Zgc:92275.
  
 
 0.621
mrps5
Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.616
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.607
gldc
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
     
 0.580
lgsn
Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family.
    
 0.576
Sod2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.571
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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