Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
lckTyrosine-protein kinase. (501 aa)    
Predicted Functional Partners:
ptprc
Protein tyrosine phosphatase receptor type C.
   
 0.876
I3KX32_ORENI
Ig-like domain-containing protein.
   
 0.838
cd79a
CD79a molecule, immunoglobulin-associated alpha.
   
 0.831
rag2
Recombination activating gene 2.
      
 0.811
cd79b
Ig-like domain-containing protein.
   
 0.790
cd247
T-cell surface glycoprotein CD3 zeta chain.
   
 0.778
LOC100709183
Uncharacterized protein.
   
 0.774
grb2
Growth factor receptor-bound protein 2b.
   
 0.774
pdgfrb
Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
    
 0.748
LOC100696446
Tyrosine-protein kinase.
  
0.747
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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