close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lckTyrosine-protein kinase. (501 aa)    
Predicted Functional Partners:
LOC100696446
Tyrosine-protein kinase.
  
0.724
CSK
Tyrosine-protein kinase.
  
0.702
CSK-2
Tyrosine-protein kinase.
  
0.697
ptprc
Protein tyrosine phosphatase receptor type C.
   
 0.684
matk
Tyrosine-protein kinase.
  
0.675
LOC100700925
RAR-related orphan receptor C.
    
 
 0.669
LOC100709183
Uncharacterized protein.
   
 0.645
LOC100701982
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
    
 0.631
grb2
Growth factor receptor-bound protein 2b.
   
0.627
pag1
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.624
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.