Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cip2aCell proliferation regulating inhibitor of protein phosphatase 2A. (899 aa)    
Predicted Functional Partners:
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.836
pacrg
PARK2 co-regulated.
    
 
 0.802
espl1
Extra spindle pole bodies like 1, separase.
   
 0.762
ska1
Spindle and kinetochore associated complex subunit 1.
   
  
 0.747
fbxo33
F-box protein 33.
      
 0.739
XRCC2
X-ray repair cross complementing 2.
      
 0.737
ppp2r1b
Protein phosphatase 2, regulatory subunit A, beta b.
    
 0.733
LOC100711605
Malate synthase-like.
   
 
 0.732
mib2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.718
topbp1
DNA topoisomerase II binding protein 1.
   
 
 0.707
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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