close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldlrLow density lipoprotein receptor a. (921 aa)    
Predicted Functional Partners:
ldlrap1
Low density lipoprotein receptor adaptor protein 1b.
    
 0.973
dab2
DAB adaptor protein 2.
    
 0.953
LOC100704334
Low density lipoprotein receptor adaptor protein 1a.
    
 0.950
LOC100692480
Si:dkey-71h2.2.
    
 0.929
LOC100711575
Low-density lipoprotein receptor isoform X2.
  
  
 
0.902
RELN
Reelin.
    
 0.826
pcsk9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.810
LOC100693720
DAB adaptor protein 1b.
    
 0.700
I3J3Q9_ORENI
DAB adaptor protein 1a.
    
 0.700
ENSONIP00000000682
Intersectin 2a.
    
 0.645
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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