Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ldlrLow density lipoprotein receptor a. (921 aa)    
Predicted Functional Partners:
ldlrap1
Low density lipoprotein receptor adaptor protein 1b.
    
 0.944
LOC100704334
Low density lipoprotein receptor adaptor protein 1a.
    
 0.914
dab2
DAB adaptor protein 2.
    
 0.913
RELN
Reelin.
    
 0.905
pcsk9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.897
LOC100692480
Si:dkey-71h2.2.
    
 0.883
ENSONIP00000065900
Si:dkey-19b23.8.
    
 0.883
mylip
Myosin regulatory light chain interacting protein a.
    
 0.874
LOC100693720
DAB adaptor protein 1b.
    
 0.829
I3J3Q9_ORENI
DAB adaptor protein 1a.
    
 0.829
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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