STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldlrap1Low density lipoprotein receptor adaptor protein 1b. (312 aa)    
Predicted Functional Partners:
ldlr
Low density lipoprotein receptor a.
    
 0.973
LOC100711575
Low-density lipoprotein receptor isoform X2.
    
 0.973
ENSONIP00000000682
Intersectin 2a.
    
  0.938
I3KKD0_ORENI
Intersectin 2b.
    
  0.938
dab2
DAB adaptor protein 2.
     
 0.916
LOC100704334
Low density lipoprotein receptor adaptor protein 1a.
  
  
 
0.901
LOC100692480
Si:dkey-71h2.2.
  
  
 
0.901
LOC100707472
AP complex subunit beta.
    
 0.885
ap1b1
AP complex subunit beta.
    
 0.869
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.762
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.