Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ldlrap1Low density lipoprotein receptor adaptor protein 1b. (312 aa)    
Predicted Functional Partners:
dab2
DAB adaptor protein 2.
     
 0.946
ldlr
Low density lipoprotein receptor a.
    
 0.944
LOC100711575
Low-density lipoprotein receptor isoform X2.
    
 0.944
stn1
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
    
   0.917
LOC100704334
Low density lipoprotein receptor adaptor protein 1a.
     
  0.916
LOC100692480
Si:dkey-71h2.2.
     
  0.915
LOC100700201
EGF-like domain-containing protein.
    
 0.913
I3J869_ORENI
EGF-like domain-containing protein.
    
 0.913
LOC100707472
AP complex subunit beta.
    
 0.912
lrp4
Low density lipoprotein receptor-related protein 4.
    
 0.911
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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