Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
foxred2FAD-dependent oxidoreductase domain containing 2. (712 aa)    
Predicted Functional Partners:
txndc16
Thioredoxin domain containing 16.
    
 
 0.949
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
    
 
 0.947
ndufaf3
NADH:ubiquinone oxidoreductase complex assembly factor.
    
   0.905
txn2
Thioredoxin 2.
 
  
 
 0.756
hmgxb4
HMG box domain containing 4a.
      
 0.755
os9
OS9 endoplasmic reticulum lectin.
    
 
 0.731
erlec1
Endoplasmic reticulum lectin 1.
    
 
 0.731
erp27
Uncharacterized protein.
    
 
 0.730
ndor1
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
   
  
 0.707
Nenf
Neudesin neurotrophic factor; Belongs to the cytochrome b5 family.
   
 
 0.701
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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