Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102078679Phosphoinositide-3-kinase, regulatory subunit 6b. (713 aa)    
Predicted Functional Partners:
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 
0.963
LOC100690007
Phosphoinositide-3-kinase regulatory subunit 5.
   
 
0.961
LOC100706781
Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.
    
  0.960
pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
  0.960
LOC100707971
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.919
LOC100702193
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.919
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.919
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
     
  0.916
I3J1D3_ORENI
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
  0.916
LOC100703527
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
     
  0.916
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (6%) [HD]