Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sergefSecretion regulating guanine nucleotide exchange factor. (405 aa)    
Predicted Functional Partners:
LOC100702351
Diphthamide biosynthesis 3.
    
 
 0.985
I3JGS7_ORENI
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
    
 
 0.866
WDR7
WD repeat domain 7.
      
 0.813
I3KXA9_ORENI
Fin bud initiation factor b.
      
 0.756
LOC100705141
Upper zone of growth plate and cartilage matrix associated b.
      
 0.755
ccdc115
Coiled-coil domain containing 115.
      
 0.740
ush1c
USH1 protein network component harmonin.
    
 
 0.719
kcnj11
Potassium inwardly-rectifying channel, subfamily J, member 11.
     
 0.713
ZFC3H1
Zinc finger C3H1-type containing.
      
 0.703
LOC100692890
RAN binding protein 2.
   
 0.700
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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