Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100692791ETS domain-containing protein. (256 aa)    
Predicted Functional Partners:
irf8
Interferon regulatory factor 8.
   
 
 0.653
LOC100711202
Four and a half LIM domains 3b.
      
 0.495
I3J1E8_ORENI
Regulatory factor X, 1a (influences HLA class II expression).
      
 0.495
ATP6
ATP synthase subunit a.
      
 0.488
myb
V-myb avian myeloblastosis viral oncogene homolog.
     
 0.458
LOC100691239
Runt-related transcription factor.
   
 0.454
Acp7
Purple acid phosphatase.
   
 
 0.415
Lin7b
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
      
 0.411
LOC100707874
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
      
 0.410
LOC100702682
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
      
 0.410
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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