Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ClpxCaseinolytic mitochondrial matrix peptidase chaperone subunit b. (628 aa)    
Predicted Functional Partners:
clpp
ATP-dependent Clp protease proteolytic subunit.
 0.999
lonp2
Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-.
 
 
 0.965
hspd1
Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family.
  
 0.885
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.873
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
     
 0.840
LOC100693141
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
   
 0.829
LOC100697245
5-aminolevulinate synthase.
   
 0.827
LONP1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.
  
 
 0.815
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
  
  
 0.790
hspa9
Heat shock protein 9; Belongs to the heat shock protein 70 family.
   
 
 0.786
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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