Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100693043Dehydrogenase/reductase (SDR family) member 13a, duplicate 3. (358 aa)    
Predicted Functional Partners:
LOC100701408
WW domain binding protein 1.
    
 
 0.734
ctsa
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 
 0.717
retsat
Retinol saturase (all-trans-retinol 13,14-reductase).
    
 0.712
pnpla4
PNPLA domain-containing protein.
     
 0.642
LOC100700192
Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.641
LOC100695684
Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.640
I3JGF1_ORENI
Uncharacterized protein.
    
 0.623
LOC100709359
Si:ch1073-13h15.3.
    
 0.623
LOC100698939
Cytochrome P450, family 20, subfamily A, polypeptide 1.
   
 
 0.561
LOC100691118
O-acyltransferase.
   
 
 0.555
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (6%) [HD]