GPRC5D protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GPRC5D

G protein-coupled receptor class C group 5 member D. (425 aa)

Predicted Functional Partners:

cmtm8

0.671

unc93a

0.504

RNF207

0.495

I3KEZ4_ORENI

0.470

wnt10b

0.467

gpr156

0.467

has2

0.459

apc2

0.441

insyn2b

0.427

cep70

0.403

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPRC5D	I3KEZ4_ORENI	ENSONIP00000010486	ENSONIP00000066402	G protein-coupled receptor class C group 5 member D.	Collagen, type VI, alpha 1.	0.470
GPRC5D	RNF207	ENSONIP00000010486	ENSONIP00000000777	G protein-coupled receptor class C group 5 member D.	Ring finger protein 207.	0.495
GPRC5D	apc2	ENSONIP00000010486	ENSONIP00000031923	G protein-coupled receptor class C group 5 member D.	APC regulator of WNT signaling pathway 2.	0.441
GPRC5D	cep70	ENSONIP00000010486	ENSONIP00000053341	G protein-coupled receptor class C group 5 member D.	Centrosomal protein 70.	0.403
GPRC5D	cmtm8	ENSONIP00000010486	ENSONIP00000043109	G protein-coupled receptor class C group 5 member D.	CKLF-like MARVEL transmembrane domain-containing protein 8.	0.671
GPRC5D	gpr156	ENSONIP00000010486	ENSONIP00000065771	G protein-coupled receptor class C group 5 member D.	Gamma-aminobutyric acid type B receptor-like.	0.467
GPRC5D	has2	ENSONIP00000010486	ENSONIP00000069278	G protein-coupled receptor class C group 5 member D.	Hyaluronan synthase 2.	0.459
GPRC5D	insyn2b	ENSONIP00000010486	ENSONIP00000050476	G protein-coupled receptor class C group 5 member D.	Protein FAM196B.	0.427
GPRC5D	unc93a	ENSONIP00000010486	ENSONIP00000033651	G protein-coupled receptor class C group 5 member D.	Unc-93 homolog A.	0.504
GPRC5D	wnt10b	ENSONIP00000010486	ENSONIP00000015294	G protein-coupled receptor class C group 5 member D.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.467
I3KEZ4_ORENI	GPRC5D	ENSONIP00000066402	ENSONIP00000010486	Collagen, type VI, alpha 1.	G protein-coupled receptor class C group 5 member D.	0.470
RNF207	GPRC5D	ENSONIP00000000777	ENSONIP00000010486	Ring finger protein 207.	G protein-coupled receptor class C group 5 member D.	0.495
apc2	GPRC5D	ENSONIP00000031923	ENSONIP00000010486	APC regulator of WNT signaling pathway 2.	G protein-coupled receptor class C group 5 member D.	0.441
cep70	GPRC5D	ENSONIP00000053341	ENSONIP00000010486	Centrosomal protein 70.	G protein-coupled receptor class C group 5 member D.	0.403
cmtm8	GPRC5D	ENSONIP00000043109	ENSONIP00000010486	CKLF-like MARVEL transmembrane domain-containing protein 8.	G protein-coupled receptor class C group 5 member D.	0.671
gpr156	GPRC5D	ENSONIP00000065771	ENSONIP00000010486	Gamma-aminobutyric acid type B receptor-like.	G protein-coupled receptor class C group 5 member D.	0.467
has2	GPRC5D	ENSONIP00000069278	ENSONIP00000010486	Hyaluronan synthase 2.	G protein-coupled receptor class C group 5 member D.	0.459
insyn2b	GPRC5D	ENSONIP00000050476	ENSONIP00000010486	Protein FAM196B.	G protein-coupled receptor class C group 5 member D.	0.427
unc93a	GPRC5D	ENSONIP00000033651	ENSONIP00000010486	Unc-93 homolog A.	G protein-coupled receptor class C group 5 member D.	0.504
wnt10b	GPRC5D	ENSONIP00000015294	ENSONIP00000010486	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	G protein-coupled receptor class C group 5 member D.	0.467