Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
henmt1HEN methyltransferase 1. (405 aa)    
Predicted Functional Partners:
I3KW58_ORENI
Tudor domain containing 9.
     
 0.793
tdrkh
Mbt domain containing 1.
     
 0.790
asz1
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
     
 0.782
pld6
Phospholipase D family, member 6.
      
 0.769
fkbp6
Peptidylprolyl isomerase.
      
 0.765
piwil2
Piwi-like RNA-mediated gene silencing 2; Belongs to the argonaute family.
    
 0.736
tdrd5
Uncharacterized protein.
    
 0.730
tdrd1
Tudor domain containing 1.
    
 0.730
mettl3
Methyltransferase like 3; Belongs to the MT-A70-like family.
      
 0.712
parn
Poly(A)-specific ribonuclease (deadenylation nuclease).
      
 0.697
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (12%) [HD]