Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fam234bFamily with sequence similarity 234 member B. (689 aa)    
Predicted Functional Partners:
tm9sf2
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
      
 0.732
I3IV21_ORENI
Actin binding Rho activating protein a.
      
 0.629
ENSONIP00000068183
Si:dkey-29b11.3.
      
 0.629
PRELID3B
PRELI domain containing 3B.
      
 0.553
Smdt1
Essential MCU regulator, mitochondrial.
      
 0.546
LOC100698144
Single-pass membrane protein with aspartate-rich tail 1b.
      
 0.546
Nedd9
Neural precursor cell expressed, developmentally down-regulated 9.
      
 0.539
I3JXJ9_ORENI
Golgi glycoprotein 1a.
      
 0.534
ENSONIP00000056241
LOW QUALITY PROTEIN: Golgi apparatus protein 1.
      
 0.534
LOC100701703
Golgi glycoprotein 1b.
      
 0.534
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (10%) [HD]