Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nol12Nucleolar protein 12. (232 aa)    
Predicted Functional Partners:
rpf2
Ribosome production factor 2 homolog.
   
 
 0.973
LOC100711132
Nucleolar protein interacting with the FHA domain of MKI67.
   
 
 0.971
Brix1
Brix domain containing 2.
   
 
 0.970
ebna1bp2
EBNA1 binding protein 2.
   
 
 0.960
noc3l
Nucleolar complex protein 3 homolog.
   
 
 0.942
ftsj3
pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
   
 
 0.941
ddx27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27; Belongs to the DEAD box helicase family.
   
 0.941
rrp8
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
   
   0.939
gnl3
Guanine nucleotide binding protein-like 3 (nucleolar).
   
 
 0.938
nop53
Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.
   
 
 0.937
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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